Phospho-gsk-3β ser9
Phospho-GSK-3beta (Ser9) Antibody detects endogenous levels of GSK-3β only when phosphorylated at serine 9. The antibody may cross-react weakly with the phosphorylated form of GSK-3α due to high sequence homology. Species Reactivity: Human, Mouse, Rat, Monkey. Species predicted to react based on 100% sequence homology: WebGSK3B is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, …
Phospho-gsk-3β ser9
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WebNov 2, 2012 · NOK could make complexes with both Akt and GSK-3β. Moreover, the expression levels of NOK, p-Akt (Thr308) and p-GSK-3β (Ser9) were positively correlated in cancerous and non-cancerous breast cell lines. Thus, our data identified a novel functional molecular complex formed by NOK, Akt and GSK-3β that may relay a NOK-directed … WebPhospho-GSK-3β (Ser9) Assay. Increased signal is observed with the titration of pGSK-3β positive cell lysate. Signal for negative lysate remains low throughout the titration. The …
WebApr 14, 2024 · Since Phosphorylation of GSK-3β at Ser9 presents the inactivity state of GSK-3β , we detected the fluorescence intensity of phosphorylated GSK-3β at Ser9. … Webimportant member of the Wnt signaling pathway, GSK-3 plays a role in cell fate in early embryonic development. GSK-3β has also been implicated in the progression of Alzheimer’s disease through the phosphorylation of the micr otubule-associated protein tau. The MSD Phospho-GSK-3β (Ser9) Assay is available on 96-well 4-Spot plates.
WebAug 17, 2024 · GSK3β is thought to be constitutively activated by autophosphorylation at Tyr216 and inactivated by phosphorylation at Ser9. The GSK3β activity has previously … WebMar 2, 2024 · Increased BDNF promotes the phosphorylation of GSK-3β at the ser9 site to inhibit GSK-3β activity through the PI3K/AKT pathway and, subsequently, tau …
WebApr 14, 2024 · Since Phosphorylation of GSK-3β at Ser9 presents the inactivity state of GSK-3β , we detected the fluorescence intensity of phosphorylated GSK-3β at Ser9. Immunofluorescence assay showed decreased intensity of GSK-3β at Ser9 in spinal dorsal horn of CFA group while TDZD-8 treatment increased the intensity of this site (Fig 3A and …
WebPhospho-GSK3 beta (Ser9) Antibody. Check out specifications and order Phospho-GSK3 beta (Ser9) Antibody online. ... Protein expression of β-catenin, GSK-3β and their phosphorylated forms, were determined by western blot analysis. Phosphorylation of β-catenin and GSK-3β was decreased after UA treatment. Erlotinib was used as the negative … high pond goat farmhow many bills were passed in 2021WebJul 3, 2024 · p-GSK-3β Antibody (Ser 9) is a goat polyclonal IgG; 200 µg/ml; or rabbit IgG; 200 µg/ml, sc-11757-R Discontinued polyclonal antibody See product citations (67) p-GSK-3β (Ser 9) has been discontinued and replaced by p-GSK-3β (F-2): sc-373800. QUICK LINKS Related Products Product Citations SEE ALSO... how many billy jack movies are thereWebSep 25, 2003 · GSK-3β is a ubiquitously expressed serine/threonine kinase that was originally discovered and named as a kinase that phosphorylates and inactivates … how many bills were introduced in 2021WebMay 11, 2024 · In addition, GSK-3β inactivation via Ser9 phosphorylation has been shown to be mediated by such kinases as cAMP-dependent protein kinase A (PKA) [10], gamma isoform of protein kinase C (PKC) [11], protein kinase D1 … high polyphenol organic olive oilWebFeb 6, 2024 · On the contrary, p-Akt ser473 and p-GSK3β ser9 of the Notch1 +/ ... In this experiment, the Akt/GSK-3β pathway was not activated in the WT RUN mice, which is … high ponytail black hairWebJul 25, 2024 · GSK-3β inactivation or GSK-3β-Ser9 phosphorylation maintains the efficiency of oxidative phosphorylation (OXPHOS) and controls the production of ROS. Ischemic preconditioning (IPC) promotes the concentration of phospho-Ser9-GSK-3β in mitochondria, which directly binds to adenine nucleotide translocator (ANT), resulting in modulation of ... how many bills were passed under biden