Jph2 molecular weight
Nettet21. jun. 2024 · Junctophilin-2 (JPH2) is a part of the junctional membrane complex that facilitates calcium-handling in the cardiomyocyte. Previously, missense variants in … Nettet15. jun. 2014 · JPH2 has emerged as a critical regulator of the complex JMC microenvironment in cardiac myocytes. It provides an anchor for developing T-tubules …
Jph2 molecular weight
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Nettet28. aug. 2024 · The number average molecular weight (M n) is given by 2.2.7 , where M i is molecular weight of a molecule of oligomer n, and N i is number of molecules of that molecular weight. Total weight = Σ ∞ i = 1MiNi. Total number = Σ ∞ i = 1Ni. Mn = Σ ∞ i = 1MiNi Σ ∞ i = 1Ni. Example 2.2.8. Nettet30. mar. 2024 · ( G) mRNA expression levels for JPH2 and CAV3. ( H) Protein expression levels determined using JPH2 (sc-51313, Santa Cruz Biotechnology) and CAV3 (ab2912, Abcam) antibodies. n = 5 per group for G and H. * P < 0.05 and ** P < 0.01 vs. the euthermic group by Student’s t test. Open in viewer Increased Expression of JPH2 and …
Nettet2. mar. 2024 · JPH2 provided by HGNC Official Full Name junctophilin 2 provided by HGNC Primary source HGNC:HGNC:14202 See related Ensembl:ENSG00000149596 MIM:605267; AllianceGenome:HGNC:14202 Gene type ... Molecular Biology Databases. Bgee database; JPH2 gene expression; BioGPS; BioGPS; NettetSingle cell type specificityi. The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The …
NettetJPH2 has 2,942 functional associations with biological entities spanning 8 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 72 datasets. Nettet1. sep. 2024 · HGNC Approved Gene Symbol: JPH2 Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:44,106,590-44,187,188 (from NCBI) Gene-Phenotype Relationships PheneGene Graphics TEXT Description
Nettet18. okt. 2024 · Junctophilin 2, as junctional membrane complex (JMC) protein, is an important regulator of the cardiac SK channels RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure loss of nuclear JP2NT function accelerates stress-induced development of hypertrophy and heart failure in mutant mice
NettetJPH2 Junctophilin-2: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes. ... Molecular weight: 74,259 Da arti demarcation dalam bahasa indonesiaNettetDeveloped by Network Experts. CEO & Founder, Josh Poretz, spent years building provider networks across the country. Struggling with expensive fragmented tools, … arti demen dalam bahasa jawaNettetJPH2_ENST00000342272 Sequences You can see various sequences for this gene: cDNA (ENST00000372980.3) Protein (JPH2) Transcript and protein aligned … banda de tlahuitoltepecNettet26. jun. 2024 · Based on western blotting, the molecular weight of JPH2-CTP is estimated to exceed 20 kDa, hence the C-terminal domain is excluded (see 2). The domain … banda de tsuruNettetJPH2 is a hot spot for mutations linked to hypertrophic cardiomyopathy (HCM) ( 15 – 17 ), and repeats in JPH3 have been found to cause Huntington disease-like 2 (HDL-2) ( 18 ). In addition, cardiac stress results in activation of calpain, which cleaves JPH2 and drives heart failure progression ( 19 – 24 ). arti demen adalahhttp://www.chem.cmu.edu/groups/berry/gcbmwd.pdf banda devouringNettetExpression of JPH2 protein in cerebral arteries was investigated using the Wes capillary electrophoresis immunoassay system (Fig. 1C). Protein lysates from whole cerebral arteries and hearts... banda destinus