High-level mammalian phenotype id
WebMay 15, 2024 · In the Mutations, Alleles and Phenotypes section (Fig. 2D), a Phenotype Overview displays high-level terms from the Mammalian Phenotype (MP) Ontology and … WebSep 4, 2024 · Willin/FRMD6 Influences Mechanical Phenotype and Neuronal Differentiation in Mammalian Cells by Regulating ERK1/2 Activity Front Cell Neurosci. 2024 Sep 4; 14:552213. ... At the biochemical level, changes in Willin/FRMD6 expression inversely affected the activity of the extracellular signal-regulated kinases (ERK) pathway and …
High-level mammalian phenotype id
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WebMouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse. Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. WebDec 28, 2024 · A majority, 123 genes, produced a low BMD phenotype, while 64 genes caused a high BMD phenotype ( Fig 2B ). In addition, 13 genes were associated with either a low or high BMD phenotype, depending on sex (Figs 2B and S1 ).
WebA higher-level MP ID represents a phenotype at a broader scale; a lower-level MP ID describes a more specific phenotype or phenotypes at a smaller scale. Analysis of more detailed phenotypes or multiple level phenotypes requires more time to obtain the results. ... MamPhEA: a web tool for mammalian phenotype enrichment analysis. Bioinformatics ... WebJun 26, 2024 · Here, we used high-throughput phenotype data from 14,250 wildtype and 40,192 mutant mice (representing 2,186 knockout lines), analysed for up to 234 traits, and found a large proportion of...
WebHER2 receptor tyrosine kinase that is overexpressed in approximately 20% of all breast cancers (BCs) is a poor prognosis factor and a precious target for BC therapy. Trastuzumab is approved by FDA to specifically target HER2 for treating HER2+ BC. However, about 60% of patients with HER2+ breast tumor develop de novo resistance to trastuzumab, partially … http://evol.nhri.org.tw/phenome/Tutorial_MamPhEA.jsp
WebMGI Marker Accession ID: Mouse Marker Symbol: NOT Designation: GO Term ID: MGI Reference Accession ID: GO Evidence Code: Inferred From: Ontology P=Biological …
WebMammalian Phenotype (MP) respiratory system phenotype: 0.0001307: Moderately Informative: Direct: Mammalian Phenotype (MP) abnormal protein level: 0.0001878: Moderately Informative: Direct: Mammalian Phenotype (MP) liver/biliary system phenotype: 0.001523: Moderately Informative: Inherited: Mammalian Phenotype (MP) abnormal … dictcursor\\u0027 object has no attribute commitWebThe meaning of HIGHER MAMMAL is any of the placental or eutherian mammals; especially : a member of the Educabilia. dict clashWebMar 14, 2024 · Term: mammalian phenotype. Definition: the observable morphological, physiological, behavioral and other characteristics of mammalian organisms that are manifested through development and lifespan. ID: MP:0000001. Phenotype Tree View. … dict.com englischWebThe Mammalian Phenotype Ontology (MP) (Smith and Eppig 2012) is essential to the integration of phenotype data in MGD. MP is a structured vocabulary whose development and continued maintenance is centered at MGD with community input. city clerk\u0027s ruling no. 15WebMar 3, 2024 · These mouse phenome-wide phenotype-phenotype association data reveal general principles of relationships among mammalian phenotypes and provide a … dictcursor\\u0027 object has no attribute lastrowidWebSep 8, 2014 · Fusokines are chimeric proteins generated by the physical coupling of cytokines in a single polypeptide, resulting in proteins with highly pleiotropic activity and the potential to treat cancer and autoimmune ailments. For instance, the fusokine GIFT15 (GM-CSF and Interleukin 15 Fusion Transgene) has been shown to be a powerful … dict class in pythonhttp://evol.nhri.org.tw/phenome/Tutorial_MamPhEA.jsp dictcursor\\u0027 object has no attribute rollback