Cyclothiomethylation
Web2,4,8-Trialkyl-3-thia-1,5-diazabicyclo[3.2.1]octanes have been obtained by the regioselective and stereoselective cyclocondensation of 1,2-ethanediamine with aldehydes RCHO (R═Me, Et, Prn, Bun, Pentn) and H2S at molar ratio 1:3:2 at 0°C. The increase in molar ratio of thiomethylation mixture RCHO–H2S (6:4) at 40°C resulted in selective formation of bis … WebThe review generalizes and systemizes published data on the synthesis of biologically active saturated five-, six-, seven-, and eight-membered S,N-heterocycles. Particular attention is given to cyclothiomethylation of various amines by the action of two-component systems CH2O-H2S (or thiols) and RCHO-CS2 (or S2Cl2).
Cyclothiomethylation
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WebJan 18, 2024 · Cyclothymia is one of three types of bipolar. Rather than experiencing alternating episodes of major depression and mania as is common in other types of … WebCyclothiomethylation of o-phenylenediamine with CH2O and H2S gives rise to 1,2,4,5-tetrahydrobenzo[d][1,3,6]thiadiazepine and 1,2,6,7-tetrahydrobenzo[f][1,3,5,8]dithiadiazonine, whereas m-phenylenediamine forms benzothiaza macroheterocycles of various structure, comprising 4–8 molecules of the starting …
WebMar 1, 2024 · Cyclothiomethylation of sulfamide using paraformaldehyde or bis (dimethylamino)methane, hydrogen sulfide or its sodium salts catalyzed by rare-earth salts affords 1,4,2,6-dithiadi azinane 1,1-dioxide. The heterocycle was found to exhibit a pronounced cytotoxic effect against suspension tumor cell lines (Jurkat, HL60, K562, and …
WebNov 19, 2007 · Cyclothiomethylation of 1a, b at 20–40 °C gives a mixture of 2a, b and 3a, b together with 3- (2-methylideneaminoethyl)-1,3-thiazetidines ( 4a, b) ( Scheme 1 ). The latter were observed by GC–MS. Mass spectra of 4a, b contain peaks of molecular ions [M] + with m / z 130 4a and 144 4b. WebCyclothiomethylation of aliphatic polyamines with formaldehyde and hydrogen sulfide
WebNov 19, 2007 · The cyclothiomethylation of carboxylic acid hydrazides RCONHNH2 (R = C5H4N, Ph, 2-MeOC6H4, or 4-HOC6H4CH2) with formaldehyde and H2S at 70 °C affords predominantly the corresponding… Expand 9 Phenylenediamine and 4,4′-diaminodiphenyls in cyclothiomethylation with CH2O and H2S G. R. Khabibullina, V. R. Akhmetova, R. …
WebJun 29, 2010 · ChemInform Abstract: Cyclothiomethylation of Primary Amines with Formaldehyde and Hydrogen Sulfide to Nitrogen‐ and Sulfur‐Containing Heterocycles Akhmetova, V. R.; Nadyrgulova, G. R.; Niatshina, Z. T.; Dzhemilev, U. M. ChemInform, Volume 41 (26) – Jun 29, 2010 Preview Only Download PDF View on Publisher Site 1 … rays te37 xt wheelsWebMay 18, 2010 · The cyclothiomethylation of carboxylic acid hydrazides RCONHNH2 (R = C5H4N, Ph, 2-MeOC6H4, or 4-HOC6H4CH2) with formaldehyde and H2S at 70 °C affords predominantly the corresponding N-(1,3,5-dithiazinan-5-yl)amides, whereas this reaction at 0–−50 °C gives a mixture of the latter compounds with 3-acyl-1,3,4-thiadiazolidines. rays te37 sonic 16インチWebJan 8, 2015 · Particular attention is given to cyclothiomethylation of various amines by the action of two-component systems CH2O-H2S (or thiols) and RCHO-CS2 (or … ray steadman allen musicWebDec 1, 2015 · The review generalizes and systemizes published data on the synthesis of biologically active saturated five-, six-, seven-, and … simply food chocolate chip cookiesWebcyclothiomethylation with CH2O and H2S with the initial reagents in ratios of 1:6:4 leads to the selective formation of 1,5-dithia-3,7-diazacyclooctanes. ray steadman bioWeb开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 simply food ecclesall roadWebJan 7, 2012 · ChemInform Abstract: Cyclothiomethylation of Heterochain α,ω‐Diamines with Formaldehyde and H2S. ChemInform Abstract: Cyclothiomethylation of Heterochain α,ω‐Diamines with Formaldehyde and H2S. simply food grantham